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Research Associate - Novasenta, A UPMC Enterprises Portfolio Company

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Description

Novasenta is a UPMC Enterprises funded biotech start-up focused on discovering novel therapeutic targets to develop innovative and effective treatments with the goal of transforming the lives of patients with cancer. 
 
The responsibility of the Research Associate is to perform laboratory activities to support the therapy development efforts of Novasenta. The goal is to partner with the scientific team to develop new cancer therapies targeting immunoregulatory mechanisms in the tumor microenvironment. This role will report to the Principal Scientist.

Responsibilities:
  • Reports to Principal Scientist to ensure meeting the goals of Novasenta and pursuing the most promising targets within the tumor microenvironment for the development of therapeutics
  • Conducts routine and non-routine lab procedures and assays for molecular, cellular and metabolic characterization of relevant samples from mouse models of cancer and human clinical cancer tissue under the supervision of Research Scientist
  • Supports the development of biological, immunological assay to investigate mechanisms of immune-mediated effects of novel identified targets
  • Supports the development and validation of new technologies for molecular, cellular and metabolic characterization of samples
  • Contributes to the profiling and validation of novel druggable immunotherapy targets
  • Documents and maintains a detailed and precise record of work performed
  • Actively participates in the scientific dialogue of the group and proactively collaborates with colleagues
What we offer you:
  • Competitive pay and benefits package.
  • A fast-paced startup culture combined with the stability of a well-established entity (UPMC).
  • Work with some of the leaders in the immunotherapy and cancer field.
  • Opportunity to be part of a growing, dynamic and diverse team of highly skilled professionals discovering novel cancer therapies and making an impact on patient care.

Qualifications

  • MS in biology, immunology or closed related field with 2+ years of experience in industry or academic research lab setting or PhD with similar background and 0-2 years of relevant experience
  • Prior biopharma industry or commercial research experience desired experience with several of the following relevant techniques:
    • Mammalian cell culture
    • Flow cytometry and cell sorting
    • Molecular biology techniques (e.g., PCR, development of genetic constructs, cloning, etc.)
    • NGS (WGS, WES or RNAseq, including preparation of genomic libraries)
    • CRISPR or other advanced genetic editing techniques
    • Processing and characterization of fresh human tumor samples
    • Cell-based metabolic assays
  • Ability to propose new experimental designs, plan and conduct laboratory experiments, and evaluate and interpret data
  • Fundamental understanding of the process of discovery and development of immunology-based therapeutic targets and possible novel therapeutic concepts
  • Experience in immuno-oncology-related animal studies is a plus
  • The role requires critical thinking e.g. by proposing and implementing novel experimental approaches and concepts contributing to the cancer immunology and immune therapy research goals.
  • The ideal candidate is product and goal oriented, focused on a career in biotech. They are highly efficient and organized and have a demonstrated ability to adhere to and follow defined timelines, milestone, and objectives.
  • Experience in working under GLP standards and ensuring safety compliance under BSL-2
  • Experience with laboratory information system (LIMS) is a plus
  • Good verbal and written communication skills and the ability to interpret, summarize, and present results in a clear, concise, accurate manner
Licensure, Certifications, and Clearances:

UPMC is an Equal Opportunity Employer/Disability/Veteran

Location: Pittsburgh, PA, United States
Job ID: 054376388

UPMC is an equal opportunity employer.
Minority / Females / Veterans / Individuals with Disabilities