Leadership & Operations

Director Portfolio Development, Translational Science

Job ID: 736915161

UPMC is an equal opportunity employer. Minority / Females / Veterans / Individuals with Disabilities


As a Translational Development leader, the individual will work closely with the Head of Portfolio Development & Translational Science leadership to identify, evaluate, develop a business-case for project proposals and enable informed decision making for investment.  For funded proposals, they will work with both internal and external team members to oversee execution of agreed plan per approved timelines and budgets with the ultimate goal of de-risking and enhancing value for commercial partnerships or new company formation.  For opportunities that require the formation of a new company, the Director will help with business-related startup activities, including the management of internal and external stakeholders contributing to the success implementation of the business plan.
This role primarily focuses on developing early stage assets or technologies that are 2-4 years from clinical entry. The Director has overall accountability for projects and is the point of contact for key stakeholders including executive management in TS Enterprises and the innovators/Principal Investigators.  Experience in a core drug development discipline (e.g. toxicology, non-clinical or clinical pharmacology, business development, etc.), leading project teams in a research or translational function, and intelligence gathering/synthesis to evaluate business opportunities are core competencies.
  • E2E accountability for internal pipeline asset management (idea to commercial) which includes,
    • proposal intake, evaluation, business case development, translational plan development and partnering with Portfolio development colleagues on executing the plan
  • Actively manages multiple programs at various stages as well as leads new proposal/concept evaluation in parallel.
  • Collaborates closely with PIs to ensure idea fits with desired program attributes for consideration and enables idea development with an understanding of potential commercial pathways.
  • Drafts and leads finalization of translational development plan for the program ensuring key questions are identified and addressed via the plan to inform future investment decision making.
  • Leads discussions on program proposals, plans and business case at internal team forums for their input and develops team recommendation to be presented at governing bodies.
  • Build partnerships with University of Pittsburgh Office of Innovation & PIs & relevant stakeholders to drive forward internal pipeline portfolio.
  • Oversee execution of agreed plans and serve as primary contact with vendors, business partners and internal stakeholders ensuring completion of agreed plan in a timely fashion.
  • Participate in external diligence on an ad-hoc basis.
  • Support organizational initiatives to accomplish Portfolio Development organizational goals and long term vision.
  • Support hiring, serve as a mentor to junior staff. Develop and coach direct reports to be future.


  • MS at a minimum, PhD in life sciences or MD preferred
  • 8 years of relevant professional experience in the life sciences or healthcare industry for MS or 5 plus years for PhD.   
  • MBA or PMP certification is a plus
  • The successful candidate should have the demonstrated ability to independently tackle complex scientific and business problems 
    • Demonstrated history of management, project planning and reporting, problem solving, organizational, and negotiation skills.  
    • Demonstrated ability to communicate (both in writing and orally) complicated scientific or medical information to a broad audience including scientific experts, business professionals and C-Level executives. 
  • We are looking for candidates with a successful track record of working in and managing small cross-functional teams, having demonstrated the capacity to effectively manage upward and downward to achieve critical project goals. 
  • The ideal candidate is a self-starter, highly motivated and willing to go the extra mile to support the vision of enabling Life Changing Medicine. 
  • Excellent written and oral communication skills required 
  • Flexibility for travel as needed   

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