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Research Associate, TTMS

Description

Purpose:
Reports to the Research Scientist to ensure they are meeting the goals of TTMS and pursuing the most promising targets within the tumor microenvironment for the development of therapeutics.

Responsibilities:

  • This includes the conduct of relevant exploratory experiments and control experiments, applying basic scientific principles.
  • Performs lab managerial, which includes ordering supplies and maintaining inventory, ensuring safety, service and maintain laboratory instruments of the lab, etc.
  • Under the direction from the Research Scientist, the candidate applies his/her technical expertise in the field of cellular and molecular immunology and cancer biology.
  • Conducts routine and non-routine lab procedures and assays for molecular, cellular and metabolic characterization of relevant samples from mouse models of cancer and human clinical cancer tissue.
  • Documents and maintains a detailed and precise record of work performed.
  • As needed, supports the development and validation of new technologies for molecular, cellular and metabolic characterization of samples.
  • Supports the development of immunological assays to investigate mechanisms of immune-mediated effects of novel identified targets.
  • Contributes to the profiling and validation of novel druggable immunotherapy targets.

 

Qualifications

-Master's Degree from an accredited institution with 0-2 years' experience in immunology or Bachelor's degree from an accredited institution and 2+ years' experience in immunology

-Prior biopharma industry or commercial research experience desired

-Experience with several of the following relevant techniques: Mammalian cell culture Flow cytometry and cell sorting Molecular biology techniques (e.g., PCR, development of genetic constructs, cloning, etc.) NGS (WGS, WES or RNAseq, including preparation of genomic libraries) CRISPR or other advanced genetic editing techniques 

-Processing and characterization of fresh human tumor samples    

-Cell-based metabolic assays

-Ability to propose new experimental designs, plan and conduct laboratory experiments, and evaluate and interpret data

-Fundamental understanding of the process of discovery and development of immunology-based therapeutic targets and possible novel therapeutic concepts

-The role requires critical thinking e.g. by proposing and implementing novel experimental approaches and concepts contributing to the cancer immunology and immune therapy research goals

-The ideal candidate is product and goal oriented, focused on a career in biotech

-They are highly efficient and organized and have a demonstrated ability to adhere to and follow defined timelines, milestone, and objectives.

-Experience in working under GLP standards and ensuring safety compliance under BSL-2

-Experience with laboratory information system (LIMS) is a plus

-Must be willing to work flexible hours as necessary, and work beyond 40hrs+ is likely to be required

Licensure, Certifications, and Clearances:

UPMC is an Equal Opportunity Employer/Disability/Veteran

 

Location: Pittsburgh, PA, United States
Job ID: 75698687

UPMC is an equal opportunity employer.
Minority / Females / Veterans / Individuals with Disabilities