Connect with us icon Connect With Us

Pre-Clinical Program Coordinator-Therapeutic Tumor Microenvironment Strategies, NewCo2

Sorry, we’re not accepting applications for this job right now. But don’t go yet! Explore our site to find more opportunities to join us in transforming the future of health care.


Provides day-to-day operational leadership and staff oversight for Therapeutic Tumor Microenvironment Strategies NewCo2, a UPMC Enterprises funded biotech startup.

  • Coordinates the development of the required lab infrastructure to perform sample preparation processes and assays
  • Determines associated program objectives, milestones and timelines and ensures strict adherence to these timelines
  • Directs and supervises the lab
  • Drives hiring of a team of technicians performing lab work/discovery research
  • Ensures compliance with all relevant regulatory standards (e.g. HIPPA, GLP/GMP)
  • Implements state-of-the art sample management and storage system
  • Must be willing to work flexible hours as necessary, and work beyond 40hrs is likely to be required
  • Oversees sample collection, processing and analysis
  • Responsible for financial planning and budgeting of lab operations
  • Runs the lab to meet operational and regulatory requirements associated with high-throughput processing of clinical samples
  • Setup of a laboratory information system (LIMS)
  • Supports the scientific and business leadership of TTMS in exploring and implementing strategic business models, including identification of commercial IP
  • Works with the scientific founders to determine specific project priorities to investigate the most promising targets within the tumor microenvironment for the development of therapeutics


·       PhD in Immunology, 5+ yrs of postdoctoral experience with increasing responsibility

·       Relevant research and discovery experience in academia or industry across key areas of immunology, supported by a strong resume and publication record, including but not limited to:

o   a. T-cell biology

o   b. Cell and/or molecular immunology

o   c. Cancer immunotherapy

o   d. Computational biology

o   e. Cancer/immune metabolic pathways

o   f. Therapeutic target discovery and validation

·       The ideal candidate would have extensive experience with the following techniques:

o   a. T-cell focused cellular and molecular immunology (e.g. flow cytometry, TCR sequencing)

o   b. Cancer immunology, including in-vitro, in-vivo (e.g., mouse models of cancer) and clinical models (e.g. analysis of human cancer samples)

o   c. Next generation sequencing (incl. WGS/WES and RNAseq, single cell analysis)

o   d. High throughput T-cell response assays

o   e. Analysis of metabolic cellular pathways (e.g. metabolic substrate analysis)

·       Experience setting up a discovery laboratory and operating sample management, storage solutions, and LIMS Experience in running a cutting edge, multidisciplinary research program or clinical laboratory

·       Experience in identifying and developing clinically actionable biomarkers, predictors and associated assays

·       The ideal candidate is product and goal oriented, focused on a career in biotech

·       They are highly efficient and organized, and have a demonstrated ability to adhere to and follow defined timelines, milestone, and objectives

·       The ideal candidate has demonstrated success in highly dynamic research and/or biotech settings

The ideal candidate can deal with uncertainty and solve problems creatively with solid judgement

Licensure, Certifications, and Clearances:
UPMC is an equal opportunity employer. Minority/Females/Veterans/Individuals with Disabilities

Location: Pittsburgh, PA, United States
Job ID: 622975

UPMC is an equal opportunity employer.
Minority / Females / Veterans / Individuals with Disabilities